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High Frequency of Either Altered Pre-Core Start Codon or Weakened Kozak Sequence in the Core Promoter Region in Hepatitis B Virus A1 Strains from Rwanda

Hepatitis B virus (HBV) is endemic in Rwanda and is a major etiologic agent for chronic liver disease in the country. In a previous analysis of HBV strains from Rwanda, the S genes of most strains segregated into one single clade of subgenotype, A1. More than half (55%) of the anti-HBe positive indi...

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Detalles Bibliográficos
Autores principales: Norder, Heléne, Twagirumugabe, Theogene, Said, Joanna, Tian, Yarong, Tang, Ka-Wei, Magnius, Lars, Lindh, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471190/
https://www.ncbi.nlm.nih.gov/pubmed/30813638
http://dx.doi.org/10.3390/genes10030182