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Pharmacokinetics and Pharmacodynamics Modeling and Simulation Systems to Support the Development and Regulation of Liposomal Drugs

Liposomal formulations have been developed to improve the therapeutic index of encapsulated drugs by altering the balance of on- and off-targeted distribution. The improved therapeutic efficacy of liposomal drugs is primarily attributed to enhanced distribution at the sites of action. The targeted d...

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Detalles Bibliográficos
Autores principales: He, Hua, Yuan, Dongfen, Wu, Yun, Cao, Yanguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471205/
https://www.ncbi.nlm.nih.gov/pubmed/30866479
http://dx.doi.org/10.3390/pharmaceutics11030110