The Opposite Effect of c-Jun Transcription Factor on Apolipoprotein E Gene Regulation in Hepatocytes and Macrophages

Apolipoprotein E (apoE) is mainly secreted by hepatocytes and incorporated into most plasma lipoproteins. Macrophages, which accumulate cholesterol and are critical for the development of the atherosclerotic plaque, are also an important, albeit smaller, apoE source. Distal regulatory elements contr...

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Detalles Bibliográficos
Autores principales: Trusca, Violeta G., Fuior, Elena V., Kardassis, Dimitris, Simionescu, Maya, Gafencu, Anca V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471215/
https://www.ncbi.nlm.nih.gov/pubmed/30909560
http://dx.doi.org/10.3390/ijms20061471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471215/
https://www.ncbi.nlm.nih.gov/pubmed/30909560
http://dx.doi.org/10.3390/ijms20061471

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