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Metabolic Inhibition Induces Transient Increase of L-type Ca(2+) Current in Human and Rat Cardiac Myocytes

Metabolic inhibition is a common condition observed during ischemic heart disease and heart failure. It is usually accompanied by a reduction in L-type Ca(2+) channel (LTCC) activity. In this study, however, we show that metabolic inhibition results in a biphasic effect on LTCC current (I(CaL)) in h...

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Detalles Bibliográficos
Autores principales: Treinys, Rimantas, Kanaporis, Giedrius, Fischmeister, Rodolphe, Jurevičius, Jonas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471217/
https://www.ncbi.nlm.nih.gov/pubmed/30917498
http://dx.doi.org/10.3390/ijms20061501