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G-Quadruplexes as An Alternative Recognition Element in Disease-Related Target Sensing

G-quadruplexes are made up of guanine-rich RNA and DNA sequences capable of forming noncanonical nucleic acid secondary structures. The base-specific sterical configuration of G-quadruplexes allows the stacked G-tetrads to bind certain planar molecules like hemin (iron (III)-protoporphyrin IX) to re...

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Detalles Bibliográficos
Autores principales: Ida, Jeunice, Chan, Soo Khim, Glökler, Jörn, Lim, Yee Ying, Choong, Yee Siew, Lim, Theam Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471233/
https://www.ncbi.nlm.nih.gov/pubmed/30893817
http://dx.doi.org/10.3390/molecules24061079