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Trypanosoma brucei Interaction with Host: Mechanism of VSG Release as Target for Drug Discovery for African Trypanosomiasis

The protozoan Trypanosoma brucei, responsible for animal and human trypanosomiasis, has a family of major surface proteases (MSPs) and phospholipase-C (PLC), both involved in some mechanisms of virulence during mammalian infections. During parasitism in the mammalian host, this protozoan is exclusiv...

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Detalles Bibliográficos
Autores principales: Moreno, Cláudia Jassica Gonçalves, Temporão, Adriana, Torres, Taffarel, Sousa Silva, Marcelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471236/
https://www.ncbi.nlm.nih.gov/pubmed/30934540
http://dx.doi.org/10.3390/ijms20061484