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Toxins Utilize the Endoplasmic Reticulum-Associated Protein Degradation Pathway in Their Intoxication Process

Several bacterial and plant AB-toxins are delivered by retrograde vesicular transport to the endoplasmic reticulum (ER), where the enzymatically active A subunit is disassembled from the holotoxin and transported to the cytosol. In this process, toxins subvert the ER-associated degradation (ERAD) pa...

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Detalles Bibliográficos
Autores principales: Nowakowska-Gołacka, Jowita, Sominka, Hanna, Sowa-Rogozińska, Natalia, Słomińska-Wojewódzka, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471375/
https://www.ncbi.nlm.nih.gov/pubmed/30875878
http://dx.doi.org/10.3390/ijms20061307