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Toxins Utilize the Endoplasmic Reticulum-Associated Protein Degradation Pathway in Their Intoxication Process
Several bacterial and plant AB-toxins are delivered by retrograde vesicular transport to the endoplasmic reticulum (ER), where the enzymatically active A subunit is disassembled from the holotoxin and transported to the cytosol. In this process, toxins subvert the ER-associated degradation (ERAD) pa...
Autores principales: | Nowakowska-Gołacka, Jowita, Sominka, Hanna, Sowa-Rogozińska, Natalia, Słomińska-Wojewódzka, Monika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471375/ https://www.ncbi.nlm.nih.gov/pubmed/30875878 http://dx.doi.org/10.3390/ijms20061307 |
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