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Plasma Rich in Growth Factors (PRGF) Disrupt the Blood-Brain Barrier Integrity and Elevate Amyloid Pathology in the Brains of 5XFAD Mice

Alzheimer’s disease (AD) is the most common neurodegenerative disorder affecting 5.4 million people in the United States. Currently approved pharmacologic interventions for AD are limited to symptomatic improvement, not affecting the underlying pathology. Therefore, the search for novel therapeutic...

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Detalles Bibliográficos
Autores principales: Duong, Quoc-Viet, Kintzing, Margia L., Kintzing, William E., Abdallah, Ihab M., Brannen, Andrew D., Kaddoumi, Amal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471393/
https://www.ncbi.nlm.nih.gov/pubmed/30934587
http://dx.doi.org/10.3390/ijms20061489