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Plasma Rich in Growth Factors (PRGF) Disrupt the Blood-Brain Barrier Integrity and Elevate Amyloid Pathology in the Brains of 5XFAD Mice
Alzheimer’s disease (AD) is the most common neurodegenerative disorder affecting 5.4 million people in the United States. Currently approved pharmacologic interventions for AD are limited to symptomatic improvement, not affecting the underlying pathology. Therefore, the search for novel therapeutic...
Autores principales: | Duong, Quoc-Viet, Kintzing, Margia L., Kintzing, William E., Abdallah, Ihab M., Brannen, Andrew D., Kaddoumi, Amal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471393/ https://www.ncbi.nlm.nih.gov/pubmed/30934587 http://dx.doi.org/10.3390/ijms20061489 |
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