λ-Carrageenan Oligosaccharides of Distinct Anti-Heparanase and Anticoagulant Activities Inhibit MDA-MB-231 Breast Cancer Cell Migration

In tumor development, the degradation of heparan sulfate (HS) by heparanase (HPSE) is associated with cell-surface and extracellular matrix remodeling as well as the release of HS-bound signaling molecules, allowing cancer cell migration, invasion and angiogenesis. Because of their structural simila...

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Detalles Bibliográficos
Autores principales: Groult, Hugo, Cousin, Rémi, Chot-Plassot, Caroline, Maura, Maheva, Bridiau, Nicolas, Piot, Jean-Marie, Maugard, Thierry, Fruitier-Arnaudin, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471403/
https://www.ncbi.nlm.nih.gov/pubmed/30818840
http://dx.doi.org/10.3390/md17030140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471403/
https://www.ncbi.nlm.nih.gov/pubmed/30818840
http://dx.doi.org/10.3390/md17030140

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