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λ-Carrageenan Oligosaccharides of Distinct Anti-Heparanase and Anticoagulant Activities Inhibit MDA-MB-231 Breast Cancer Cell Migration
In tumor development, the degradation of heparan sulfate (HS) by heparanase (HPSE) is associated with cell-surface and extracellular matrix remodeling as well as the release of HS-bound signaling molecules, allowing cancer cell migration, invasion and angiogenesis. Because of their structural simila...
Autores principales: | Groult, Hugo, Cousin, Rémi, Chot-Plassot, Caroline, Maura, Maheva, Bridiau, Nicolas, Piot, Jean-Marie, Maugard, Thierry, Fruitier-Arnaudin, Ingrid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471403/ https://www.ncbi.nlm.nih.gov/pubmed/30818840 http://dx.doi.org/10.3390/md17030140 |
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