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Halogen-Substituted Triazolethioacetamides as a Potent Skeleton for the Development of Metallo-β-Lactamase Inhibitors

Metallo-β-lactamases (MβLs) are the target enzymes of β-lactam antibiotic resistance, and there are no effective inhibitors against MβLs available for clinic so far. In this study, thirteen halogen-substituted triazolethioacetamides were designed and synthesized as a potent skeleton of MβLs inhibito...

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Detalles Bibliográficos
Autores principales:	Zhang, Yilin, Yan, Yong, Liang, Lufan, Feng, Jie, Wang, Xuejun, Li, Li, Yang, Kewu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471427/ https://www.ncbi.nlm.nih.gov/pubmed/30934584 http://dx.doi.org/10.3390/molecules24061174

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