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Prenatal nicotine exposure induces depression-like behavior in adolescent female rats via modulating neurosteroid in the hippocampus

Prenatal nicotine exposure (PNE) is closely related to depression in offspring. However, the underlying mechanism is still unclear. We hypothesized that neurosteroid in the hippocampus may mediate PNE-induced depression-like behaviors. Nicotine was subcutaneously administered (1.0 mg/kg) to pregnant...

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Detalles Bibliográficos
Autores principales: Zhang, Chong, Fan, Si-Jing, Sun, An-Bang, Liu, Zhen-Zhen, Liu, Lian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471439/
https://www.ncbi.nlm.nih.gov/pubmed/30942466
http://dx.doi.org/10.3892/mmr.2019.10105