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Biological Evaluation and Docking Analysis of Potent BACE1 Inhibitors from Boesenbergia rotunda

Alzheimer’s disease (AD) is an irreversible neurodegenerative disorder characterized by progressive impairment of cognitive functions. Beta-site amyloid precursor protein cleaving enzyme1 (BACE1) is essential for the formation of β-amyloid peptide (Aβ), a major constituent of amyloid plaques that re...

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Detalles Bibliográficos
Autores principales: Youn, Kumju, Jun, Mira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471523/
https://www.ncbi.nlm.nih.gov/pubmed/30893825
http://dx.doi.org/10.3390/nu11030662