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Biological Evaluation and Docking Analysis of Potent BACE1 Inhibitors from Boesenbergia rotunda
Alzheimer’s disease (AD) is an irreversible neurodegenerative disorder characterized by progressive impairment of cognitive functions. Beta-site amyloid precursor protein cleaving enzyme1 (BACE1) is essential for the formation of β-amyloid peptide (Aβ), a major constituent of amyloid plaques that re...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471523/ https://www.ncbi.nlm.nih.gov/pubmed/30893825 http://dx.doi.org/10.3390/nu11030662 |