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Design and Synthesis of a New Soluble Natural β-Carboline Derivative for Preclinical Study by Intravenous Injection

Harmine is a natural β-carboline compound showing several biological activities, including antiproliferative properties, but this soluble natural molecule lacks selectivity. Harmine derivatives were reported to overcome this problem, but they are usually poorly soluble. Here, we designed and synthes...

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Detalles Bibliográficos
Autores principales: Marx, Sébastien, Bodart, Laurie, Tumanov, Nikolay, Wouters, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471559/
https://www.ncbi.nlm.nih.gov/pubmed/30934601
http://dx.doi.org/10.3390/ijms20061491