QT Assessment in Early Drug Development: The Long and the Short of It

The QT interval occupies a pivotal role in drug development as a surface biomarker of ventricular repolarization. The electrophysiologic substrate for QT prolongation coupled with reports of non-cardiac drugs producing lethal arrhythmias captured worldwide attention from government regulators eventu...

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Detalles Bibliográficos
Autores principales: Lester, Robert M., Paglialunga, Sabina, Johnson, Ian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471571/
https://www.ncbi.nlm.nih.gov/pubmed/30884748
http://dx.doi.org/10.3390/ijms20061324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471571/
https://www.ncbi.nlm.nih.gov/pubmed/30884748
http://dx.doi.org/10.3390/ijms20061324

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