Design and Synthesis of Novel Heterocyclic-Based 4H-benzo[h]chromene Moieties: Targeting Antitumor Caspase 3/7 Activities and Cell Cycle Analysis

Novel fused chromenes (4,7–11) and pyrimidines (12–16) were designed, synthesized, and evaluated for their mammary gland breast cancer (MCF-7), human colon cancer (HCT-116), and liver cancer (HepG-2) activities. The structural identity of the synthesized compounds was established according to their...

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Detalles Bibliográficos
Autores principales: Alblewi, Fawzia F., Okasha, Rawda M., Eskandrani, Areej A., Afifi, Tarek H., Mohamed, Hany M., Halawa, Ahmed H., Fouda, Ahmed M., Al-Dies, Al-Anood M., Mora, Ahmed, El-Agrody, Ahmed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471608/
https://www.ncbi.nlm.nih.gov/pubmed/30889862
http://dx.doi.org/10.3390/molecules24061060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471608/
https://www.ncbi.nlm.nih.gov/pubmed/30889862
http://dx.doi.org/10.3390/molecules24061060

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