GenHap: a novel computational method based on genetic algorithms for haplotype assembly

BACKGROUND: In order to fully characterize the genome of an individual, the reconstruction of the two distinct copies of each chromosome, called haplotypes, is essential. The computational problem of inferring the full haplotype of a cell starting from read sequencing data is known as haplotype asse...

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Detalles Bibliográficos
Autores principales: Tangherloni, Andrea, Spolaor, Simone, Rundo, Leonardo, Nobile, Marco S., Cazzaniga, Paolo, Mauri, Giancarlo, Liò, Pietro, Merelli, Ivan, Besozzi, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471693/
https://www.ncbi.nlm.nih.gov/pubmed/30999845
http://dx.doi.org/10.1186/s12859-019-2691-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471693/
https://www.ncbi.nlm.nih.gov/pubmed/30999845
http://dx.doi.org/10.1186/s12859-019-2691-y

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