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GenHap: a novel computational method based on genetic algorithms for haplotype assembly
BACKGROUND: In order to fully characterize the genome of an individual, the reconstruction of the two distinct copies of each chromosome, called haplotypes, is essential. The computational problem of inferring the full haplotype of a cell starting from read sequencing data is known as haplotype asse...
Autores principales: | Tangherloni, Andrea, Spolaor, Simone, Rundo, Leonardo, Nobile, Marco S., Cazzaniga, Paolo, Mauri, Giancarlo, Liò, Pietro, Merelli, Ivan, Besozzi, Daniela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471693/ https://www.ncbi.nlm.nih.gov/pubmed/30999845 http://dx.doi.org/10.1186/s12859-019-2691-y |
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