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RIP-Chip analysis supports different roles for AGO2 and GW182 proteins in recruiting and processing microRNA targets
BACKGROUND: MicroRNAs (miRNAs) are small non-coding RNA molecules mediating the translational repression and degradation of target mRNAs in the cell. Mature miRNAs are used as a template by the RNA-induced silencing complex (RISC) to recognize the complementary mRNAs to be regulated. To discern furt...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471694/ https://www.ncbi.nlm.nih.gov/pubmed/30999843 http://dx.doi.org/10.1186/s12859-019-2683-y |