RIP-Chip analysis supports different roles for AGO2 and GW182 proteins in recruiting and processing microRNA targets

BACKGROUND: MicroRNAs (miRNAs) are small non-coding RNA molecules mediating the translational repression and degradation of target mRNAs in the cell. Mature miRNAs are used as a template by the RNA-induced silencing complex (RISC) to recognize the complementary mRNAs to be regulated. To discern furt...

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Detalles Bibliográficos
Autores principales: Perconti, Giovanni, Rubino, Patrizia, Contino, Flavia, Bivona, Serena, Bertolazzi, Giorgio, Tumminello, Michele, Feo, Salvatore, Giallongo, Agata, Coronnello, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471694/
https://www.ncbi.nlm.nih.gov/pubmed/30999843
http://dx.doi.org/10.1186/s12859-019-2683-y

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