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Walking pathways with positive feedback loops reveal DNA methylation biomarkers of colorectal cancer

BACKGROUND: The search for molecular biomarkers of early-onset colorectal cancer (CRC) is an important but still quite challenging and unsolved task. Detection of CpG methylation in human DNA obtained from blood or stool has been proposed as a promising approach to a noninvasive early diagnosis of C...

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Detalles Bibliográficos
Autores principales: Kel, Alexander, Boyarskikh, Ulyana, Stegmaier, Philip, Leskov, Leonid S., Sokolov, Andrey V., Yevshin, Ivan, Mandrik, Nikita, Stelmashenko, Daria, Koschmann, Jeannette, Kel-Margoulis, Olga, Krull, Mathias, Martínez-Cardús, Anna, Moran, Sebastian, Esteller, Manel, Kolpakov, Fedor, Filipenko, Maxim, Wingender, Edgar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471696/
https://www.ncbi.nlm.nih.gov/pubmed/30999858
http://dx.doi.org/10.1186/s12859-019-2687-7