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The anticancer effects of cinobufagin on hepatocellular carcinoma Huh-7 cells are associated with activation of the p73 signaling pathway

The Na(+)/K(+)-ATPase inhibitor cinobufagin exhibits numerous anticancer effects on hepatocellular carcinoma (HCC) cells expressing wild-type p53 via inhibition of aurora kinase A (AURKA) and activation of p53 signaling. However, the effects of cinobufagin on HCC cells expressing mutant p53 remain u...

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Detalles Bibliográficos
Autores principales: Zhao, Lei, Fu, Lina, Xu, Zhongwei, Fan, Rong, Xu, Ruicheng, Fu, Rong, Zou, Shuang, Wang, Congcong, Zhang, Yan, Wang, Jiabao, Bao, Jun, Wang, Zhimei, Hou, Xiaojie, Zheng, Yupiao, Dai, Erqing, Wang, Fengmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471725/
https://www.ncbi.nlm.nih.gov/pubmed/30942456
http://dx.doi.org/10.3892/mmr.2019.10108