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The anticancer effects of cinobufagin on hepatocellular carcinoma Huh-7 cells are associated with activation of the p73 signaling pathway
The Na(+)/K(+)-ATPase inhibitor cinobufagin exhibits numerous anticancer effects on hepatocellular carcinoma (HCC) cells expressing wild-type p53 via inhibition of aurora kinase A (AURKA) and activation of p53 signaling. However, the effects of cinobufagin on HCC cells expressing mutant p53 remain u...
Autores principales: | Zhao, Lei, Fu, Lina, Xu, Zhongwei, Fan, Rong, Xu, Ruicheng, Fu, Rong, Zou, Shuang, Wang, Congcong, Zhang, Yan, Wang, Jiabao, Bao, Jun, Wang, Zhimei, Hou, Xiaojie, Zheng, Yupiao, Dai, Erqing, Wang, Fengmei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471725/ https://www.ncbi.nlm.nih.gov/pubmed/30942456 http://dx.doi.org/10.3892/mmr.2019.10108 |
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