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Biological Evaluation and Molecular Dynamics Simulation of Chalcone Derivatives as Epidermal Growth Factor-Tyrosine Kinase Inhibitors

Targeted cancer therapy has become a high potential cancer treatment. Epidermal growth factor receptor (EGFR), which plays an important role in cell signaling, enhanced cell survival and proliferation, has been suggested as molecular target for the development of novel cancer therapeutics. In this s...

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Detalles Bibliográficos
Autores principales: Sangpheak, Kanyani, Tabtimmai, Lueacha, Seetaha, Supaphorn, Rungnim, Chompoonut, Chavasiri, Warinthorn, Wolschann, Peter, Choowongkomon, Kiattawee, Rungrotmongkol, Thanyada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471738/
https://www.ncbi.nlm.nih.gov/pubmed/30897725
http://dx.doi.org/10.3390/molecules24061092