Catalytic Asymmetric Fluorination of Alkyl 1-indanone-2-carboxylates Ruled by Pybox-Eu(III) Combination

A highly enantioselective catalytic method for the synthesis of quaternary α-fluoro derivatives of 3-oxo esters is described. The reaction uses europium (III) triflate and commercially available chiral pybox-type C2-symmetric ligand. Excellent results in terms of yields and enantioselectivities were...

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Detalles Bibliográficos
Autores principales: Granados, Albert, Sarró, Pau, Vallribera, Adelina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471818/
https://www.ncbi.nlm.nih.gov/pubmed/30909403
http://dx.doi.org/10.3390/molecules24061141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471818/
https://www.ncbi.nlm.nih.gov/pubmed/30909403
http://dx.doi.org/10.3390/molecules24061141

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