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Uptake in the Central Nervous System of Geraniol Oil Encapsulated in Chitosan Oleate Following Nasal and Oral Administration

The pharmacological activities of geraniol include anticancer and neuroprotective properties. However, its insolubility in water easily induces separation from aqueous formulations, causing administration difficulties. Here we propose new emulsified formulations of geraniol by using the amphiphilic...

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Detalles Bibliográficos
Autores principales: Bonferoni, Maria Cristina, Ferraro, Luca, Pavan, Barbara, Beggiato, Sarah, Cavalieri, Elena, Giunchedi, Paolo, Dalpiaz, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471858/
https://www.ncbi.nlm.nih.gov/pubmed/30832389
http://dx.doi.org/10.3390/pharmaceutics11030106