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Formulation Development of Albendazole-Loaded Self-Microemulsifying Chewable Tablets to Enhance Dissolution and Bioavailability

Albendazole is an anthelmintic agent with poor solubility and absorption. We developed a chewable tablet (200 mg drug equivalent), containing a self-microemulsifying drug delivery system (SMEDDS), with oral disintegrating properties. The emulsion was developed using sesame and soybean oils along wit...

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Detalles Bibliográficos
Autores principales: Sawatdee, Somchai, Atipairin, Apichart, Sae Yoon, Attawadee, Srichana, Teerapol, Changsan, Narumon, Suwandecha, Tan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471907/
https://www.ncbi.nlm.nih.gov/pubmed/30897738
http://dx.doi.org/10.3390/pharmaceutics11030134