DHFR Inhibitors: Reading the Past for Discovering Novel Anticancer Agents

Dihydrofolate reductase inhibitors are an important class of drugs, as evidenced by their use as antibacterial, antimalarial, antifungal, and anticancer agents. Progress in understanding the biochemical basis of mechanisms responsible for enzyme selectivity and antiproliferative effects has renewed...

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Detalles Bibliográficos
Autores principales: Raimondi, Maria Valeria, Randazzo, Ornella, La Franca, Mery, Barone, Giampaolo, Vignoni, Elisa, Rossi, Daniela, Collina, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471984/
https://www.ncbi.nlm.nih.gov/pubmed/30909399
http://dx.doi.org/10.3390/molecules24061140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471984/
https://www.ncbi.nlm.nih.gov/pubmed/30909399
http://dx.doi.org/10.3390/molecules24061140

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