Target Identification of the Marine Natural Products Dictyoceratin-A and -C as Selective Growth Inhibitors in Cancer Cells Adapted to Hypoxic Environments

Hypoxia-adapted cancer cells in tumors contribute to the pathological progression of cancer. The marine spongean sesquiterpene phenols dictyoceratin-A (1) and -C (2) have been shown to induce hypoxia-selective growth inhibition in cultured cancer cells and exhibit in vivo antitumor effects. These co...

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Detalles Bibliográficos
Autores principales: Kawachi, Takashi, Tanaka, Shun, Fukuda, Akinori, Sumii, Yuji, Setiawan, Andi, Kotoku, Naoyuki, Kobayashi, Motomasa, Arai, Masayoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471994/
https://www.ncbi.nlm.nih.gov/pubmed/30857246
http://dx.doi.org/10.3390/md17030163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471994/
https://www.ncbi.nlm.nih.gov/pubmed/30857246
http://dx.doi.org/10.3390/md17030163

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