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Anti-CD166/4-1BB chimeric antigen receptor T cell therapy for the treatment of osteosarcoma
BACKGROUND: Chimeric antigen receptor (CAR)-engineered T cells have displayed outstanding performance in the treatment of patients with hematological malignancies. However, their efficacy against solid tumors has been largely limited. METHODS: In this study, human osteosarcoma cell lines were prepar...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471997/ https://www.ncbi.nlm.nih.gov/pubmed/30995926 http://dx.doi.org/10.1186/s13046-019-1147-6 |