Decreased Protein Kinase C-β Type II Associated with the Prominent Endotoxin Exhaustion in the Macrophage of FcGRIIb−/− Lupus Prone Mice is Revealed by Phosphoproteomic Analysis

Dysfunction of FcGRIIb, the only inhibitory receptor of the FcGR family, is commonly found in the Asian population and is possibly responsible for the extreme endotoxin exhaustion in lupus. Here, the mechanisms of prominent endotoxin (LPS) tolerance in FcGRIIb−/− mice were explored on bone marrow-de...

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Detalles Bibliográficos
Autores principales: Ondee, Thunnicha, Jaroonwitchawan, Thiranut, Pisitkun, Trairak, Gillen, Joseph, Nita-Lazar, Aleksandra, Leelahavanichkul, Asada, Somparn, Poorichaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472018/
https://www.ncbi.nlm.nih.gov/pubmed/30889825
http://dx.doi.org/10.3390/ijms20061354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472018/
https://www.ncbi.nlm.nih.gov/pubmed/30889825
http://dx.doi.org/10.3390/ijms20061354

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