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Deep undepleted human serum proteome profiling toward biomarker discovery for Alzheimer’s disease
BACKGROUND: Blood-based protein measurement is a routine practice for detecting biomarkers in human disease. Comprehensive profiling of blood/plasma/serum proteome is a challenge due to an extremely large dynamic range, as exemplified by a small subset of highly abundant proteins. Antibody-based dep...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472024/ https://www.ncbi.nlm.nih.gov/pubmed/31019427 http://dx.doi.org/10.1186/s12014-019-9237-1 |