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Deep undepleted human serum proteome profiling toward biomarker discovery for Alzheimer’s disease

BACKGROUND: Blood-based protein measurement is a routine practice for detecting biomarkers in human disease. Comprehensive profiling of blood/plasma/serum proteome is a challenge due to an extremely large dynamic range, as exemplified by a small subset of highly abundant proteins. Antibody-based dep...

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Detalles Bibliográficos
Autores principales: Dey, Kaushik Kumar, Wang, Hong, Niu, Mingming, Bai, Bing, Wang, Xusheng, Li, Yuxin, Cho, Ji-Hoon, Tan, Haiyan, Mishra, Ashutosh, High, Anthony A., Chen, Ping-Chung, Wu, Zhiping, Beach, Thomas G., Peng, Junmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472024/
https://www.ncbi.nlm.nih.gov/pubmed/31019427
http://dx.doi.org/10.1186/s12014-019-9237-1