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Discovery of 2-Substituted 3-Arylquinoline Derivatives as Potential Anti-Inflammatory Agents Through Inhibition of LPS-Induced Inflammatory Responses in Macrophages

We describe herein the preparation of certain 2-substituted 3-arylquinoline derivatives and the evaluation of their anti-inflammatory effects in LPS-activated murine J774A.1 macrophage cells. Among these newly synthesized 2-substituted 3-arylquinoline derivatives, 2-(4-methoxy- benzoyl)-3-(3,4,5-tri...

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Detalles Bibliográficos
Autores principales: Yang, Cheng-Yao, Hung, Yung-Li, Tang, Kai-Wei, Wang, Shu-Chi, Tseng, Chih-Hua, Tzeng, Cherng-Chyi, Liu, Po-Len, Li, Chia-Yang, Chen, Yeh-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472047/
https://www.ncbi.nlm.nih.gov/pubmed/30909606
http://dx.doi.org/10.3390/molecules24061162