WNT3a and WNT5a Transported by Exosomes Activate WNT Signaling Pathways in Human Cardiac Fibroblasts

WNT signaling plays an important role in fibrotic processes in the heart. Recently, exosomes have been proposed as novel extracellular transporters for WNT proteins. In this study, we analyzed whether WNT3a and WNT5a carried by exosomes could activate downstream molecular pathways in human cardiac f...

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Detalles Bibliográficos
Autores principales: Działo, Edyta, Rudnik, Michał, Koning, Roman I., Czepiel, Marcin, Tkacz, Karolina, Baj-Krzyworzeka, Monika, Distler, Oliver, Siedlar, Maciej, Kania, Gabriela, Błyszczuk, Przemysław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472055/
https://www.ncbi.nlm.nih.gov/pubmed/30901906
http://dx.doi.org/10.3390/ijms20061436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472055/
https://www.ncbi.nlm.nih.gov/pubmed/30901906
http://dx.doi.org/10.3390/ijms20061436

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