Antifibrotic effects of 2-carba cyclic phosphatidic acid (2ccPA) in systemic sclerosis: contribution to the novel treatment

BACKGROUND: Cyclic phosphatidic acid (cPA) has an inhibitory effect on the autotaxin (ATX)/lysophosphatidic acid (LPA) axis, which has been implicated to play an important role in the progression of fibrosis in systemic sclerosis (SSc). The purpose of this study is to assess the antifibrotic activit...

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Detalles Bibliográficos
Autores principales: Higuchi, Tomoaki, Takagi, Kae, Tochimoto, Akiko, Ichimura, Yuki, Norose, Takanari, Katsumata, Yasuhiro, Masuda, Ikuko, Yamanaka, Hisashi, Morohoshi, Toshiro, Kawaguchi, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472078/
https://www.ncbi.nlm.nih.gov/pubmed/30999934
http://dx.doi.org/10.1186/s13075-019-1881-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472078/
https://www.ncbi.nlm.nih.gov/pubmed/30999934
http://dx.doi.org/10.1186/s13075-019-1881-3

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