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Caveolin-1 regulation of Sp1 controls production of the antifibrotic protein follistatin in kidney mesangial cells

BACKGROUND: We previously showed that caveolin-1 (cav-1), an integral membrane protein, is required for the synthesis of matrix proteins by glomerular mesangial cells (MC). In a previous study to understand how cav-1 is involved in regulating matrix production, we had identified significant upregula...

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Detalles Bibliográficos
Autores principales: Mehta, Neel, Zhang, Dan, Li, Renzhong, Wang, Tony, Gava, Agata, Parthasarathy, Pavithra, Gao, Bo, Krepinsky, Joan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472091/
https://www.ncbi.nlm.nih.gov/pubmed/30995923
http://dx.doi.org/10.1186/s12964-019-0351-5