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Circular RNA hsa_circ_0068871 regulates FGFR3 expression and activates STAT3 by targeting miR-181a-5p to promote bladder cancer progression

BACKGROUND: FGFR3 plays an important role in the development of bladder cancer (BCa). Hsa_circ_0068871 is a circRNA generated from several exons of FGFR3. However, the potential functional role of hsa_circ_0068871 in BCa remains largely unknown. Here we aim to evaluate the role of hsa_circ_0068871 i...

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Detalles Bibliográficos
Autores principales: Mao, Weipu, Huang, Xin, Wang, Longsheng, Zhang, Ziwei, Liu, Mengnan, Li, Yan, Luo, Ming, Yao, Xudong, Fan, Jie, Geng, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472097/
https://www.ncbi.nlm.nih.gov/pubmed/30999937
http://dx.doi.org/10.1186/s13046-019-1136-9