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1,25-Dihydroxy-Vitamin D3 induces macrophage polarization to M2 by upregulating T-cell Ig-mucin-3 expression

Macrophage polarization serves an important role in immune regulation that is regulated by T-cell immunoglobulin-mucin-3 (Tim-3). The objective of the present study was to explore the role of 1,25-dihydroxy-vitamin D3 [1,25(OH)(2)D3] in macrophage polarization. Plasmid transfection techniques were a...

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Detalles Bibliográficos
Autores principales: Liang, Shuyu, Cai, Jinzhen, Li, Yani, Yang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472136/
https://www.ncbi.nlm.nih.gov/pubmed/30896850
http://dx.doi.org/10.3892/mmr.2019.10047