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Role of Arginase 2 in Systemic Metabolic Activity and Adipose Tissue Fatty Acid Metabolism in Diet-Induced Obese Mice

Visceral adipose tissue (VAT) inflammation and metabolic dysregulation are key components of obesity-induced metabolic disease. Upregulated arginase, a ureahydrolase enzyme with two isoforms (A1-cytosolic and A2-mitochondrial), is implicated in pathologies associated with obesity and diabetes. This...

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Detalles Bibliográficos
Autores principales: Atawia, Reem T., Toque, Haroldo A., Meghil, Mohamed M., Benson, Tyler W., Yiew, Nicole K. H., Cutler, Christopher W., Weintraub, Neal L., Caldwell, Ruth B., Caldwell, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472154/
https://www.ncbi.nlm.nih.gov/pubmed/30909461
http://dx.doi.org/10.3390/ijms20061462