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From trash to treasure: detecting unexpected contamination in unmapped NGS data
BACKGROUND: Next Generation Sequencing (NGS) experiments produce millions of short sequences that, mapped to a reference genome, provide biological insights at genomic, transcriptomic and epigenomic level. Typically the amount of reads that correctly maps to the reference genome ranges between 70% a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472186/ https://www.ncbi.nlm.nih.gov/pubmed/30999839 http://dx.doi.org/10.1186/s12859-019-2684-x |