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From trash to treasure: detecting unexpected contamination in unmapped NGS data

BACKGROUND: Next Generation Sequencing (NGS) experiments produce millions of short sequences that, mapped to a reference genome, provide biological insights at genomic, transcriptomic and epigenomic level. Typically the amount of reads that correctly maps to the reference genome ranges between 70% a...

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Detalles Bibliográficos
Autores principales: Sangiovanni, Mara, Granata, Ilaria, Thind, Amarinder Singh, Guarracino, Mario Rosario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472186/
https://www.ncbi.nlm.nih.gov/pubmed/30999839
http://dx.doi.org/10.1186/s12859-019-2684-x