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decompTumor2Sig: identification of mutational signatures active in individual tumors
BACKGROUND: The somatic mutations found in a tumor have in most cases been caused by multiple mutational processes such as those related to extrinsic carcinogens like cigarette smoke, and those related to intrinsic processes like age-related spontaneous deamination of 5-methylcytosine. The effect of...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472187/ https://www.ncbi.nlm.nih.gov/pubmed/30999866 http://dx.doi.org/10.1186/s12859-019-2688-6 |