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Reconstitution of the lipid-linked oligosaccharide pathway for assembly of high-mannose N-glycans
The asparagine (N)-linked Man9GlcNAc2 is required for glycoprotein folding and secretion. Understanding how its structure contributes to these functions has been stymied by our inability to produce this glycan as a homogenous structure of sufficient quantities for study. Here, we report the high yie...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472349/ https://www.ncbi.nlm.nih.gov/pubmed/31000718 http://dx.doi.org/10.1038/s41467-019-09752-3 |