BRD9 binds cell type-specific chromatin regions regulating leukemic cell survival via STAT5 inhibition

Leukemia is characterized by genetic and epigenetic mutations resulting in selection of cancer cells, which are unable to differentiate. Although genetic alterations are difficult to target, the epigenome is intrinsically dynamic and readily offers new therapeutic strategies. Thus, identifying cance...

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Detalles Bibliográficos
Autores principales: Del Gaudio, Nunzio, Di Costanzo, Antonella, Liu, Ning Qing, Conte, Lidio, Migliaccio, Antimo, Vermeulen, Michiel, Martens, Joost H. A., Stunnenberg, Hendrik G., Nebbioso, Angela, Altucci, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472371/
https://www.ncbi.nlm.nih.gov/pubmed/31000698
http://dx.doi.org/10.1038/s41419-019-1570-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472371/
https://www.ncbi.nlm.nih.gov/pubmed/31000698
http://dx.doi.org/10.1038/s41419-019-1570-9

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