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Identifying A- and P-site locations on ribosome-protected mRNA fragments using Integer Programming

Identifying the A- and P-site locations on ribosome-protected mRNA fragments from Ribo-Seq experiments is a fundamental step in the quantitative analysis of transcriptome-wide translation properties at the codon level. Many analyses of Ribo-Seq data have utilized heuristic approaches applied to a na...

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Detalles Bibliográficos
Autores principales: Ahmed, Nabeel, Sormanni, Pietro, Ciryam, Prajwal, Vendruscolo, Michele, Dobson, Christopher M., O’Brien, Edward P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472398/
https://www.ncbi.nlm.nih.gov/pubmed/31000737
http://dx.doi.org/10.1038/s41598-019-42348-x