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Identifying A- and P-site locations on ribosome-protected mRNA fragments using Integer Programming
Identifying the A- and P-site locations on ribosome-protected mRNA fragments from Ribo-Seq experiments is a fundamental step in the quantitative analysis of transcriptome-wide translation properties at the codon level. Many analyses of Ribo-Seq data have utilized heuristic approaches applied to a na...
Autores principales: | Ahmed, Nabeel, Sormanni, Pietro, Ciryam, Prajwal, Vendruscolo, Michele, Dobson, Christopher M., O’Brien, Edward P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472398/ https://www.ncbi.nlm.nih.gov/pubmed/31000737 http://dx.doi.org/10.1038/s41598-019-42348-x |
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