Nicotinamide mononucleotide promotes osteogenesis and reduces adipogenesis by regulating mesenchymal stromal cells via the SIRT1 pathway in aged bone marrow

Mesenchymal stromal cells (MSCs) can differentiate to various cell types including osteoblasts, chondrocytes, and adipocytes. This cellular flexibility contributes to widespread clinical use of MSCs in tissue repair. However, challenges remain in efficient cellular expansion of MSCs for stem cell th...

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Detalles Bibliográficos
Autores principales: Song, Jie, Li, Jing, Yang, Fangji, Ning, Gang, Zhen, Limin, Wu, Lina, Zheng, Yongyuan, Zhang, Qi, Lin, Dongjun, Xie, Chan, Peng, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472410/
https://www.ncbi.nlm.nih.gov/pubmed/31000692
http://dx.doi.org/10.1038/s41419-019-1569-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472410/
https://www.ncbi.nlm.nih.gov/pubmed/31000692
http://dx.doi.org/10.1038/s41419-019-1569-2

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