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Drug prioritization using the semantic properties of a knowledge graph

Compounds that are candidates for drug repurposing can be ranked by leveraging knowledge available in the biomedical literature and databases. This knowledge, spread across a variety of sources, can be integrated within a knowledge graph, which thereby comprehensively describes known relationships b...

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Detalles Bibliográficos
Autores principales: Malas, Tareq B., Vlietstra, Wytze J., Kudrin, Roman, Starikov, Sergey, Charrout, Mohammed, Roos, Marco, Peters, Dorien J. M., Kors, Jan A., Vos, Rein, ‘t Hoen, Peter A. C., van Mulligen, Erik M., Hettne, Kristina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472420/
https://www.ncbi.nlm.nih.gov/pubmed/31000794
http://dx.doi.org/10.1038/s41598-019-42806-6